Botanical Name : Holarrhena Antidysenterica
Sanskrit Name: Kutaj                                  
English Name : Connessi bark, Tellicherry bark  
Family : Apocynaceae                                          
Part used: Bark , Seed             

About Holarrhena Antidysenterica:
It is a large tree of 30 to 40 feet in height. Its flowers color white and fruits of half inch in size.

Phytochemical properties:

Around 30 alkaloids have been isolated from the plant, mostly from the bark. These include conessine, kurchine, kurchicine, holarrhimine, conarrhimine, conaine, conessimine, iso-conessimine, conimine, holacetin and conkurchin.
Conessine from the bark killed free living amoebae and also kills entamoeba histolytica in the dysenteric stools of experimentally infected kittens. It is markedly lethal to the flagellate protozoon. It is antitubercular Conkurchine is hydrochloride hypotensive and vasodilator. Different experiments showed that its aqueous and alcoholic extracts inhibited the growth of different enteric organisms like staphylococcus aureus, vibrio cholerae 01 & 0139, enteroinvasive and enteropathogenic E.coli, species of Shigella, Salmonella typhimurium, S. enteriditis, Klebsiella spp, Proteus mirabilis, Aeromonas spp, Citrobacter freundii,Staphylococcus aureus and Pseudomonas aeruginosa.

Medicinal Uses:

It is one of the best drug for diarrhoea. In chronic diarrhoea & to check blood coming from stool, it should be given with Isobgol, caster oil or Indrayav.
According to Ayurveda, the bark is useful in treatment of piles, skin diseases and biliousness.
The bark is used externally in case of skin troubles. The bark is mostly mixed with cow urine and applies it in affected parts. In treatment of urinary troubles, the bark is given with cow milk. The fresh juice of bark is considered good to check the diarrhoea. In bleeding piles Decoction of Kutaj bark with sunthi checks mucus & blood. Application of this herb is useful in Rh. Arthritis & Osteoarthritis. The bark is used in chest affections and as a remedy in diseases of the skin and spleen. It is a well known herb for amoebic dysentery and other gastric disorders.

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